Faculty of Environmental Engineering and Graduate School of Environmental Engineering
The University of Kitakyushu
|Department||Department of Life and Environment Engineering|
|sakurai[ at ]kitakyu-u.ac.jp
＊Please change "[at]" to "@".
|Education||1982 BS, Polymer Science, Department of Science, Osaka University.
1984 MS, Polymer Science, Department of Science, Osaka University.
1996 PhD, Polymer Science, Department of Science, Osaka University.
|Employment History||1985-1990 Research Scientist in Kanebo Ltd.,
1990-1993 Visiting Researcher in University of Mass, Amherst
1994-1995 Research Scientist in Kanebo Ltd.,
1995-2000 Research Group leader of Kanebo Ltd.,
1999-2000 JST Shinkai ICORP project Group leader
2000-2001 JST PREST Researcher
2001- Professor (The University of Kitakyushu)
|Teaching Activities||Organic Chemistry, Physical Chemistry, X-ray Scattering|
|Research Interest||Characterization of Polysaccharide/DNA complexes and its application to gene delivery, Synthesis and characterization of novel cationic liposome for plasmid DNA delivery, Synchrotron small-angle X-ray scattering from DNA complexes|
|Publications||1, himada N, Coban C, Takeda Y, Mizu M, Minari J, Anada T, Torii Y, Shinkai S, Akira S, Ishii KJ, Sakurai K. "A polysaccharide carrier to effectively deliver native phosphodiester CpG DNA to antigen-presenting cells" Bioconjug Chem, 18, 1280-6 (2007)
2, Shimada N, Ishii KJ, Takeda Y, Coban C, Torii Y, Shinkai S, Akira S, Sakurai K. "Synthesis and in vitro characterization of antigen-conjugated polysaccharide as a CpG DNA carrier" Bioconjug Chem, 17, 1136-40 (2006)
3, Karinaga R, Anada T, Minari J, Mizu M, Koumoto K, Fukuda J, Nakazawa K, Hasegawa T, Numata M, Shinkai S, Sakurai K. "Galactose-PEG dual conjugation of beta-(1-->3)-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake" Biomaterials, 27, 1626-35 (2006)
4, Minari, Jusaku; Mochizuki, Shinichi; Matsuzaki, Tsubasa; Adachi, Yoshiyuki; Ohno, Naohito; Sakurai, Kazuo. Enhanced Cytokine Secretion from Primary Macrophages due to Dectin-1 Mediated Uptake of CpG DNA/β-1,3-glucan Complex. Bioconjugate Chemistry. Vol.22, 1, p9-15 (2011)
|Other activities||Advanced Softmaterial Beamline Consortium Organizing Committee Chair|